Topic Summaries

The kidney

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Stem cells, microscopy, and microorganisms

Pathogens and non-specific immunity

Plant disease and monoclonal antibodies

Resource cycles and environmental change

  • The kidneys produce urine by filtration of the blood and selective reabsorption of useful substances, such as glucose, water and some ions.
  • The water balance in the body is controlled by the hormone ADH which increases the permeability of kidney tubules. ADH is released by the pituitary gland when the blood is too concentrated, causing more water to be reabsorbed back into the blood from the kidney tubules (i.e. negative feedback as more ADH is released when the blood is more concentrated).
  • Kidney failure happens when a person’s kidneys are no longer able to filter their blood effectively and can lead to toxicity. Kidney dialysis can be used to treat kidney failure temporarily by the removal of high levels of urea. This involves filtering the blood through a dialysis machine to diffuse urea out of the blood before it is returned to the body.

  • An organ transplant can be used to treat kidney failure as humans have two kidneys and only require one to survive, so a living person can donate a kidney for transplant.
  • The body may treat the kidney as foreign and the body’s immune system may attack it. Immunosuppressant drugs are given to the patient to reduce the chances of rejection; however, these weaken their immune system.

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